Exploring Brain Connectivity in Youth with Obsessive-Compulsive Disorder
Funded by the National Institute of Mental Health (NIMH)
A pilot version of the current study explored brain differences between adolescents with OCD and those without the disorder. Findings revealed that youths with OCD exhibit differences in brain connectivity when compared to adolescents without OCD.
The purpose of the current study is to explore the effects of sertraline (an FDA-approved medication for children with OCD) on brain connectivity in children and adolescents with OCD. We hypothesize that sertraline will normalize the abnormalities in brain connectivity seen in youths with OCD.
Possible changes in brain connectivity will be measured with MRI scans before and after 12 weeks of sertraline. Participants receiving sertraline will be seen regularly by the study's Principal Investigator, Dr. Bernstein.